Staphylococcus epidermidis - a new player in acne pathogenesis?
Acne is a chronic and multifactorial inflammatory disease of the skin and hair and sebaceous unit. Studies have shown that between the ages of 11 and 30 years, 80 % people can be affected by this condition. The pathogenesis of acne is extremely complex. Causes causing acne vulgaris may include seborrhoea, hyperkeratinisation of the hair and sebaceous glands, hormonal factors, increased inflammation and colonisation of the sebaceous units by Cutibacterium acnes bacteria. Dysbiosis in patients with acne is associated with reduced numbers of S. epidermidis cells and excessive colonisation of the sebaceous unit by C. acnes cells
Recent studies appear to confirm the beneficial role of S. epidermidis in acne pathogenesis by reducing skin colonisation and inflammation caused by C. acnes.
Acne-prone skin requires proper, comprehensive and systematic care. Innovative acne cosmetics are expected to be able to improve the skin microbiome - restoring the balance between S. epidermidis and C. acnes. This will reduce inflammation and improve the condition of the skin.
How then to design a study able to demonstrate the efficacy of a product against acne?
At MPR Science, we offer innovative tests for acne skin care cosmetics - Efficacy assessment against C. acnes (tests performed in vitro) and S. epidermidis viability test (tests performed in vitro and in vivo). The methodology of our analyses is based on the latest scientific findings.
The right choice of analyses is the key to success in creating cosmetic products that not only meet consumers' expectations but also contribute to the health of their skin.
Need to design a study for your products? Write to us!